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Milestones
- 2004: Portrayed 'Peter Pan' author J.M. Barrie in "Finding Neverland" also starring Kate Winslet; received a Golden Globe, SAG and an Oscar nomination for Best Actor
- 2004: Plays a writer who is accused of plagiarism by a strange man, who then starts haunting him in "The Secret Window"
- 2004: Received a People's Choice nomination for Favorite movie actor
- 2003: Starred in the blockbuster hit "Pirates of the Caribbean: The Curse of the Black Pearl"; earned a Golden Globe nomination for best actor in a comedy or musical; received an Academy Award nomination for Best Actor
- 2003: Earned a People's Choice nomination for "Favorite movie actor"
- 2003: Played a sociopathic CIA agent in the Robert Rodriguez western feature "Once Upon A Time In Mexico"
- 2001: Portrayed American George Jung, one of the major cocaine traffickers for Columbian kingpin Pablo Escobar, in Ted Demme's "Blow"
- 2001: Cast as British policeman with unorthodox means of tracking a serial killer in the thriller "From Hell", about the "Jack the Ripper" murders in London
- 2000: Had two roles in Julian Schnabel's "Before Night Falls", the biopic of gay Cuban writer Reinaldo Arenas; played an imprisoned drag queen with a gift for smuggling and a brutally officious army officer
- 2000: Played a gold-toothed Gypsy in love with Ricci in Sally Potter's World War II drama "The Man Who Cried"; screened at Venice; released in USA in 2001
- 1999: Starred opposite Charlize Theron in the thriller "The Astronaut's Wife"
- 1999: Reteamed with Burton for "Sleepy Hollow", loosely based on the Washington Irving story; played opposite Christina Ricci
- 1999: Received star on the Hollywood Walk of Fame (November 16)
- 1999: Starred as corruptible rare-book dealer hired to find satanic texts in Roman Polanski's supernatural thriller "The Ninth Gate" (released in USA in March 2000)
- 1998: Portrayed Raoul Duke in Terry Gilliam's adaptation of "Fear and Loathing in Las Vegas"; first film with Christina Ricci
- 1997: Earned some of the best reviews of his career as the title character in "Donnie Brasco"; based on the book about an FBI agent who infiltrated the Mob
- 1997: Feature directorial debut, "The Brave", reteamed him with Brando; also wrote and co-starred; premiered at the Cannes Film Festival; Pop wrote the score
- 1996: Starred as William Blake in Jim Jarmusch's post-modern Western "Dead Man"; film also featured Iggy Pop
- 1995: Made first action film, John Badham's "Nick of Time"; cast as a mild-mannered accountant who becomes embroiled in an assassination scheme
- 1995: Formed the rock group P, making major label debut on Capitol Records
- 1995: Acted opposite Marlon Brando in "Don Juan DeMarco"
- 1995: Purchased first home in Los Angeles; house once owned by Bela Lugosi
- 1994: Directed the eight-minute short film "Banter" for DARE (Drug Abuse Resistance Education)
- 1994: Played infamous, cross-dressing, B-movie director "Ed Wood"; second film with Burton
- 1993: Impressively recreated silent-comedy routines of Charlie Chaplin and Buster Keaton in "Benny and Joon"
- 1993: Opened L.A. club, The Viper Room
- 1993: Starred in the title role of "What's Eating Gilbert Grape"
- 1992: Appeared along with Jerry Lewis and Faye Dunaway in Emir Kusturica's "Arizona Dream"
- 1990: First hit movie, Tim Burton's "Edward Scissorhands", co-starring then-girlfriend Winona Ryder
- 1990: Headlined John Waters' "Cry-Baby", playing Elvis-inspired, leather-clad title role; first film acting with Iggy Pop
- From 1987 to 1990: Starred as a baby-faced undercover cop in TV series, "21 Jump Street" (Fox)
- 1987: Began working with the Make-A-Wish Foundation (date approximate)
- 1986: TV-movie debut, "Slow Burn" (Showtime)
- 1986: Had small role in Oliver Stone's "Platoon"
- 1985: TV acting debut in episode of "Lady Blue" (ABC)
- 1985: First screen lead, "Private Resort"
- 1984: Introduced by his then-wife Lori Allison to actor Nicolas Cage, who in turn arranged a meeting with an agent; agent set up audition for feature acting debut in Wes Craven's "A Nightmare on Elm Street"; the director's daughter Jessica also played a part in convincing her father to cast Depp
- 1983: Moved to Los Angeles with band, The Kids; played lead guitar
- 1969: Moved to Miramar, Florida
- ---: Starred as a 17th century poet in "The Libertine" (lensed 2004)
- ---: Cast as Willy Wonka, in Tim Burton's remake of the classic tale "Charlie and the Chocolate Factory" (lensed 2004)
- Reteamed with Terry Gilliam to play a modern-day ad executive whisked back in time in "The Man Who Killed Don Quixote"; shooting began in 2000 but was put on hold when leading actor Jean Rochefort suffered a double disc hernia
- Sold ball-point pens by phone before he began acting
- Started own rock group at age 13; subsequently played in 15 other bands
- Will reprise role of journalist Hunter S. Thompson, in "The Rum Diary," based on Thompson's very first novel, which journals his career and personal escapades in 1950's Puerto Rico (lensed 2005)
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